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Hydroxyurea‐induced denaturation of normal and sickle cell hemoglobins in vitro

Use of hydroxyurea (HU) to treat sickle cell disease is usually associated with increments in fetal hemoglobin (Hb F) production; however, in vitro studies show that HU may also induce hemoglobin denaturation. Whole blood samples from Hb AA, Hb AS, and Hb SS patients were treated in vitro with 100,...

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Detaylı Bibliyografya
Yayımlandı:J Clin Lab Anal
Asıl Yazarlar: Roa, D., Kopsombut, P., Aguinaga, M. d. P., Turner, E. A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wiley Subscription Services, Inc., A Wiley Company 1998
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760688/
https://ncbi.nlm.nih.gov/pubmed/9219062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/(SICI)1098-2825(1997)11:4<208::AID-JCLA6>3.0.CO;2-4
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