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Hydroxyurea‐induced denaturation of normal and sickle cell hemoglobins in vitro
Use of hydroxyurea (HU) to treat sickle cell disease is usually associated with increments in fetal hemoglobin (Hb F) production; however, in vitro studies show that HU may also induce hemoglobin denaturation. Whole blood samples from Hb AA, Hb AS, and Hb SS patients were treated in vitro with 100,...
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| Publicado no: | J Clin Lab Anal |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6760688/ https://ncbi.nlm.nih.gov/pubmed/9219062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/(SICI)1098-2825(1997)11:4<208::AID-JCLA6>3.0.CO;2-4 |
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