Can the Orexin Antagonist Suvorexant Preserve the Ability to Awaken to Auditory Stimuli While Improving Sleep?

STUDY OBJECTIVES: The safety profile of the dual orexin receptor antagonists (DORAs) are currently unknown with regard to nocturnal responsivity among people with insomnia. We compared the auditory awakening thresholds (AATs) of the DORA suvorexant (10 and 20 mg) versus placebo in 12 individuals wit...

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Pubblicato in:J Clin Sleep Med
Autori principali: Drake, Christopher L., Kalmbach, David A., Cheng, Philip, Roth, Thomas, Tran, Kieulinh Michelle, Cuamatzi-Castelan, Andrea, Atkinson, Rachel, Singh, Meeta, Tonnu, Christine V., Fellman-Couture, Cynthia
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Academy of Sleep Medicine 2019
Soggetti:
Scientific Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760418/
https://ncbi.nlm.nih.gov/pubmed/31538599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5664/jcsm.7920
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