Can the Orexin Antagonist Suvorexant Preserve the Ability to Awaken to Auditory Stimuli While Improving Sleep?

STUDY OBJECTIVES: The safety profile of the dual orexin receptor antagonists (DORAs) are currently unknown with regard to nocturnal responsivity among people with insomnia. We compared the auditory awakening thresholds (AATs) of the DORA suvorexant (10 and 20 mg) versus placebo in 12 individuals wit...

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Udgivet i:J Clin Sleep Med
Main Authors: Drake, Christopher L., Kalmbach, David A., Cheng, Philip, Roth, Thomas, Tran, Kieulinh Michelle, Cuamatzi-Castelan, Andrea, Atkinson, Rachel, Singh, Meeta, Tonnu, Christine V., Fellman-Couture, Cynthia
Format: Artigo
Sprog:Inglês
Udgivet: American Academy of Sleep Medicine 2019
Fag:
Scientific Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760418/
https://ncbi.nlm.nih.gov/pubmed/31538599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5664/jcsm.7920
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