Can the Orexin Antagonist Suvorexant Preserve the Ability to Awaken to Auditory Stimuli While Improving Sleep?

STUDY OBJECTIVES: The safety profile of the dual orexin receptor antagonists (DORAs) are currently unknown with regard to nocturnal responsivity among people with insomnia. We compared the auditory awakening thresholds (AATs) of the DORA suvorexant (10 and 20 mg) versus placebo in 12 individuals wit...

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Опубликовано в: :J Clin Sleep Med
Главные авторы: Drake, Christopher L., Kalmbach, David A., Cheng, Philip, Roth, Thomas, Tran, Kieulinh Michelle, Cuamatzi-Castelan, Andrea, Atkinson, Rachel, Singh, Meeta, Tonnu, Christine V., Fellman-Couture, Cynthia
Формат: Artigo
Язык:Inglês
Опубликовано: American Academy of Sleep Medicine 2019
Предметы:
Scientific Investigations
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760418/
https://ncbi.nlm.nih.gov/pubmed/31538599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5664/jcsm.7920
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