Dietary Fiber-Induced Microbial Short Chain Fatty Acids Suppress ILC2-Dependent Airway Inflammation

Group 2 Innate lymphoid cells (ILC2) contribute significantly to allergic inflammation. However, the role of microbiota on ILC2s remains to be unraveled. Here we show that short chain fatty acids (SCFAs), such as butyrate, derived from fermentation of dietary fibers by the gut microbiota inhibit pul...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lewis, Gavin, Wang, Bowen, Shafiei Jahani, Pedram, Hurrell, Benjamin P., Banie, Homayon, Aleman Muench, German R., Maazi, Hadi, Helou, Doumet Georges, Howard, Emily, Galle-Treger, Lauriane, Lo, Richard, Santosh, Swetha, Baltus, Andrew, Bongers, Gerrold, San-Mateo, Lani, Gilliland, Frank D., Rehan, Virender K., Soroosh, Pejman, Akbari, Omid
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760365/
https://ncbi.nlm.nih.gov/pubmed/31620118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02051
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