GH Knockout Mice Have Increased Subcutaneous Adipose Tissue With Decreased Fibrosis and Enhanced Insulin Sensitivity

In 1997, our laboratory used targeted gene disruption of the GH receptor (GHR) to generate GHR knockout (GHR(−/−)) mice, which have been used in >127 published studies to help elucidate GH’s numerous activities. However, because GH replacement studies cannot be performed using this line, a GH kno...

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Vydáno v:Endocrinology
Hlavní autoři: List, Edward O, Berryman, Darlene E, Buchman, Mathew, Jensen, Elizabeth A, Funk, Kevin, Duran-Ortiz, Silvana, Qian, Yanrong, Young, Jonathan A, Slyby, Julie, McKenna, Savannah, Kopchick, John J
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2019
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760334/
https://ncbi.nlm.nih.gov/pubmed/31099824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2019-00167
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