GH Knockout Mice Have Increased Subcutaneous Adipose Tissue With Decreased Fibrosis and Enhanced Insulin Sensitivity

In 1997, our laboratory used targeted gene disruption of the GH receptor (GHR) to generate GHR knockout (GHR(−/−)) mice, which have been used in >127 published studies to help elucidate GH’s numerous activities. However, because GH replacement studies cannot be performed using this line, a GH kno...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: List, Edward O, Berryman, Darlene E, Buchman, Mathew, Jensen, Elizabeth A, Funk, Kevin, Duran-Ortiz, Silvana, Qian, Yanrong, Young, Jonathan A, Slyby, Julie, McKenna, Savannah, Kopchick, John J
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760334/
https://ncbi.nlm.nih.gov/pubmed/31099824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2019-00167
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