Drivers of AR indifferent anti-androgen resistance in prostate cancer cells

Inhibition of the androgen receptor (AR) by second-generation anti-androgens is a standard treatment for metastatic castration resistant prostate cancer (mCRPC), but it inevitably leads to the development of resistance. Since the introduction of highly efficient AR signalling inhibitors, approximate...

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Publicat a:Sci Rep
Autors principals: Handle, Florian, Prekovic, Stefan, Helsen, Christine, Van den Broeck, Thomas, Smeets, Elien, Moris, Lisa, Eerlings, Roy, Kharraz, Sarah El, Urbanucci, Alfonso, Mills, Ian G., Joniau, Steven, Attard, Gerhardt, Claessens, Frank
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760229/
https://ncbi.nlm.nih.gov/pubmed/31551480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50220-1
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