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UVB-induced DHODH upregulation, which is driven by STAT3, is a promising target for chemoprevention and combination therapy of photocarcinogenesis

The leading cause of cutaneous squamous cell carcinomas (cSCCs) is exposure to ultraviolet radiation (UV). Unlike most other cancers, the incidence rates of cSCCs are still on the rise and the treatment options currently available are limited. We have recently found that dihydroorotate dehydrogenase...

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書目詳細資料
發表在:Oncogenesis
Main Authors: Hosseini, Mohsen, Dousset, Léa, Michon, Pauline, Mahfouf, Walid, Muzotte, Elodie, Bergeron, Vanessa, Bortolotto, Doriane, Rossignol, Rodrigue, Moisan, François, Taieb, Alain, Bouzier-Sore, Anne-Karine, Rezvani, Hamid R.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760220/
https://ncbi.nlm.nih.gov/pubmed/31551419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-019-0161-z
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