UVB-induced DHODH upregulation, which is driven by STAT3, is a promising target for chemoprevention and combination therapy of photocarcinogenesis

The leading cause of cutaneous squamous cell carcinomas (cSCCs) is exposure to ultraviolet radiation (UV). Unlike most other cancers, the incidence rates of cSCCs are still on the rise and the treatment options currently available are limited. We have recently found that dihydroorotate dehydrogenase...

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Pubblicato in:Oncogenesis
Autori principali: Hosseini, Mohsen, Dousset, Léa, Michon, Pauline, Mahfouf, Walid, Muzotte, Elodie, Bergeron, Vanessa, Bortolotto, Doriane, Rossignol, Rodrigue, Moisan, François, Taieb, Alain, Bouzier-Sore, Anne-Karine, Rezvani, Hamid R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760220/
https://ncbi.nlm.nih.gov/pubmed/31551419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-019-0161-z
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