Pd-Catalyzed de Novo Assembly of Diversely Substituted Indole-Fused Polyheterocycles

[Image: see text] Here we describe a facile, tandem synthetic route for indolo[3,2-c]quinolinones, a class of natural alkaloid analogues of high biological significance. A Ugi four-component reaction with indole-2-carboxylic acid and an aniline followed by a Pd-catalyzed cyclization yields tetracycl...

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Bibliografiset tiedot
Julkaisussa:J Org Chem
Päätekijät: Wang, Qian, Osipyan, Angelina, Konstantinidou, Markella, Butera, Roberto, Mgimpatsang, Kumchok C., Shishkina, Svitlana V., Dömling, Alexander
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2019
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759776/
https://ncbi.nlm.nih.gov/pubmed/31433186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b01258
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