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Pd-Catalyzed de Novo Assembly of Diversely Substituted Indole-Fused Polyheterocycles
[Image: see text] Here we describe a facile, tandem synthetic route for indolo[3,2-c]quinolinones, a class of natural alkaloid analogues of high biological significance. A Ugi four-component reaction with indole-2-carboxylic acid and an aniline followed by a Pd-catalyzed cyclization yields tetracycl...
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| Publicado no: | J Org Chem |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2019
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6759776/ https://ncbi.nlm.nih.gov/pubmed/31433186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b01258 |
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