Renoprotection Provided by Additional Diuretic Treatment in Partially Nephrectomized Ren-2 Transgenic Rats Subjected to the Combined RAS and ET(A) Blockade

OBJECTIVE: Our previous study in heterozygous Ren-2 transgenic rats (TGR) demonstrated that long-term treatment with endothelin receptor A (ET(A)) blocker atrasentan added to the renin-angiotensin system (RAS) blockade had renoprotective effects in a model of chronic kidney disease (CKD) induced by...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Vaněčková, Ivana, Hojná, Silvie, Vernerová, Zdenka, Kadlecová, Michaela, Rauchová, Hana, Kompanowska-Jezierska, Elzbieta, Vaňourková, Zdeňka, Červenka, Luděk, Zicha, Josef
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759492/
https://ncbi.nlm.nih.gov/pubmed/31620007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01145
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