Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats

1. The aim of the present study was to test the hypothesis that increasing kidney tissue concentrations of epoxyeicosatrienoic acids (EETs) by preventing their degradation to the biologically inactive dihydroxyeicosatrienoic acids (DHETEs) using blockade of soluble epoxide hydrolase (sEH) would atte...

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Detalhes bibliográficos
Main Authors: Kujal, Petr, Čertíková Chábová, Vera, Škaroupková, Petra, Husková, Zuzana, Vernerová, Zdena, Kramer, Herbert J, Walkowska, Agnieszka, Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Kitada, Kento, Nishiyama, Akira, Hwang, Sung H, Hammock, Bruce D, Imig, John D, Červenka, Ludek
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038339/
https://ncbi.nlm.nih.gov/pubmed/24471737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1440-1681.12204
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