Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats

1. The aim of the present study was to test the hypothesis that increasing kidney tissue concentrations of epoxyeicosatrienoic acids (EETs) by preventing their degradation to the biologically inactive dihydroxyeicosatrienoic acids (DHETEs) using blockade of soluble epoxide hydrolase (sEH) would atte...

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Autors principals: Kujal, Petr, Čertíková Chábová, Vera, Škaroupková, Petra, Husková, Zuzana, Vernerová, Zdena, Kramer, Herbert J, Walkowska, Agnieszka, Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Kitada, Kento, Nishiyama, Akira, Hwang, Sung H, Hammock, Bruce D, Imig, John D, Červenka, Ludek
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2014
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038339/
https://ncbi.nlm.nih.gov/pubmed/24471737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1440-1681.12204
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