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Enjoy the Silence: X-Chromosome Inactivation Diversity in Somatic Cells

The imbalance of sex chromosomes between females (XX) and males (XY) necessitates strict regulation of X-linked gene expression. X-Chromosome Inactivation (XCI) selects one X for transcriptional silencing in the early embryo, generating an epigenetically distinct and transcriptionally silent X that...

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Bibliografiske detaljer
Udgivet i:Curr Opin Genet Dev
Main Authors: Sierra, Isabel, Anguera, Montserrat C.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759402/
https://ncbi.nlm.nih.gov/pubmed/31108425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2019.04.012
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