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Enjoy the Silence: X-Chromosome Inactivation Diversity in Somatic Cells
The imbalance of sex chromosomes between females (XX) and males (XY) necessitates strict regulation of X-linked gene expression. X-Chromosome Inactivation (XCI) selects one X for transcriptional silencing in the early embryo, generating an epigenetically distinct and transcriptionally silent X that...
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| Udgivet i: | Curr Opin Genet Dev |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6759402/ https://ncbi.nlm.nih.gov/pubmed/31108425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2019.04.012 |
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