Llwytho...

A phosphorylation-deficient mutant of retinoid X receptor α at Thr167 alters fasting response and energy metabolism in mice

Retinoid X receptor α (RXRα) has a conserved phosphorylation motif at threonine 162 (humans) and threonine 167 (mice) within the DNA binding domain. Here we have generated RXRα knock-in mice (Rxrα(T167A)) bearing a single mutation of Thr167 to alanine and examined the roles of Thr167 in the regulati...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Lab Invest
Prif Awduron: Sueyoshi, Tatsuya, Sakuma, Tsutomu, Shindo, Sawako, Fashe, Muluneh, Kanayama, Tomohiko, Ray, Manas, Moore, Rick, Negishi, Masahiko
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759383/
https://ncbi.nlm.nih.gov/pubmed/31152145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-019-0266-1
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