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Phosphorylation of serine 212 confers novel activity to human estrogen receptor α

Estrogen receptor α (ERα) can be phosphorylated at various residues, one of which is serine 212 in the DNA binding domain. The majority of human nuclear receptors conserves, as a motif, this serine residue within their DNA binding domain. Among these nuclear receptors, phosphorylation of the corresp...

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Bibliographic Details
Main Authors: Shindo, Sawako, Sakuma, Tsutomu, Negishi, Masahiko, Squires, James
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033595/
https://ncbi.nlm.nih.gov/pubmed/22266331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2012.01.001
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