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Cancer vaccine strategies: translation from mice to human clinical trials
We translated two cancer vaccine strategies from mice into human clinical trials. (1) In preclinical studies on TARP, an antigen expressed in most prostate cancers, we mapped epitopes presented by HLA-A*0201, modified them to increase affinity and immunogenicity in HLA transgenic mice, and induced h...
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| Publicado no: | Cancer Immunol Immunother |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6759211/ https://ncbi.nlm.nih.gov/pubmed/29143114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-017-2084-x |
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