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Cancer vaccine strategies: translation from mice to human clinical trials
We translated two cancer vaccine strategies from mice into human clinical trials. (1) In preclinical studies on TARP, an antigen expressed in most prostate cancers, we mapped epitopes presented by HLA-A*0201, modified them to increase affinity and immunogenicity in HLA transgenic mice, and induced h...
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| Publié dans: | Cancer Immunol Immunother |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer Berlin Heidelberg
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6759211/ https://ncbi.nlm.nih.gov/pubmed/29143114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-017-2084-x |
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