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Erythropoietin Is a Paracrine Mediator of Ischemic Tolerance in the Brain: Evidence from an In Vitro Model

In an in vitro model of cerebral ischemia (oxygen glucose deprivation, OGD) we investigated whether erythropoietin (EPO) plays a critical role in ischemic preconditioning. We found that EPO time and dose-dependently induced protection against OGD in rat primary cortical neurons. Protection was signi...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Ruscher, Karsten, Freyer, Dorette, Karsch, Maria, Isaev, Nikolai, Megow, Dirk, Sawitzki, Birgit, Priller, Josef, Dirnagl, Ulrich, Meisel, Andreas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758760/
https://ncbi.nlm.nih.gov/pubmed/12451129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-23-10291.2002
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