A functional role of the cyclin-dependent kinase inhibitor 1 (p21(WAF1/CIP1)) for neuronal preconditioning

Hypoxic preconditioning is thought to rely on gene products regulated by hypoxia-inducible factor (HIF)-1. Here, we show that the HIF-1 target gene cyclin-dependent kinase inhibitor 1, p21(WAF1/CIP1), is essential for neuroprotection by hypoxic/aglycemic or erythropoietin preconditioning using wild-...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Mergenthaler, Philipp, Muselmann, Claudia, Sünwoldt, Juliane, Isaev, Nickolay K, Wieloch, Tadeusz, Dirnagl, Ulrich, Meisel, Andreas, Ruscher, Karsten
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2013
विषय:
Brief Communication
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587824/
https://ncbi.nlm.nih.gov/pubmed/23299246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.213
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