Mitochondrial hexokinase II (HKII) and phosphoprotein enriched in astrocytes (PEA15) form a molecular switch governing cellular fate depending on the metabolic state

The metabolic state of a cell is a key determinant in the decision to live and proliferate or to die. Consequently, balanced energy metabolism and the regulation of apoptosis are critical for the development and maintenance of differentiated organisms. Hypoxia occurs physiologically during developme...

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Detalhes bibliográficos
Main Authors: Mergenthaler, Philipp, Kahl, Anja, Kamitz, Anne, van Laak, Vincent, Stohlmann, Katharina, Thomsen, Susanne, Klawitter, Heiko, Przesdzing, Ingo, Neeb, Lars, Freyer, Dorette, Priller, Josef, Collins, Tony J., Megow, Dirk, Dirnagl, Ulrich, Andrews, David W., Meisel, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277118/
https://ncbi.nlm.nih.gov/pubmed/22233811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108225109
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