Repetitive Mild Brain Trauma Accelerates Aβ Deposition, Lipid Peroxidation, and Cognitive Impairment in a Transgenic Mouse Model of Alzheimer Amyloidosis

Traumatic brain injury (TBI) increases susceptibility to Alzheimer's disease (AD), but it is not known how TBI contributes to the onset or progression of this common late life dementia. To address this question, we studied neuropathological and behavioral consequences of single versus repetitiv...

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Gepubliceerd in:J Neurosci
Hoofdauteurs: Uryu, Kunihiro, Laurer, Helmut, McIntosh, Tracy, Praticò, Domenico, Martinez, Daniel, Leight, Susan, Lee, Virginia M.-Y., Trojanowski, John Q.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2002
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758680/
https://ncbi.nlm.nih.gov/pubmed/11784789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-02-00446.2002
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