ERK MAP Kinase Activation in Superficial Spinal Cord Neurons Induces Prodynorphin and NK-1 Upregulation and Contributes to Persistent Inflammatory Pain Hypersensitivity

Activation of ERK (extracellular signal-regulated kinase) MAP (mitogen-activated protein) kinase in dorsal horn neurons of the spinal cord by peripheral noxious stimulation contributes to short-term pain hypersensitivity. We investigated ERK activation by peripheral inflammation and its involvement...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ji, Ru-Rong, Befort, Katia, Brenner, Gary J., Woolf, Clifford J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2002
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758654/
https://ncbi.nlm.nih.gov/pubmed/11784793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-02-00478.2002
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