Bradykinin Enhances AMPA and NMDA Receptor Activity in Spinal Cord Dorsal Horn Neurons by Activating Multiple Kinases to Produce Pain Hypersensitivity

Bradykinin potentiates synaptic glutamate release and action in the spinal cord via presynaptic and postsynaptic B(2) receptors, contributing thereby to activity-dependent central sensitization and pain hypersensitivity (Wang et al., 2005). We have now examined the signaling pathways that are respon...

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Detalhes bibliográficos
Main Authors: Kohno, Tatsuro, Wang, Haibin, Amaya, Fumimasa, Brenner, Gary J., Cheng, Jen-Kun, Ji, Ru-Rong, Woolf, Clifford J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653863/
https://ncbi.nlm.nih.gov/pubmed/18434532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5349-07.2008
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