Bradykinin Produces Pain Hypersensitivity by Potentiating Spinal Cord Glutamatergic Synaptic Transmission

Bradykinin, an inflammatory mediator, sensitizes nociceptor peripheral terminals reducing pain threshold. We now show that the B(2) kinin receptor is expressed in rat dorsal horn neurons and that bradykinin, a B(2)-specific agonist, augments AMPA- and NMDA-induced, and primary afferent-evoked EPSCs,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Neurosci
मुख्य लेखकों: Wang, Haibin, Kohno, Tatsuro, Amaya, Fumimasa, Brenner, Gary J., Ito, Nobuko, Allchorne, Andrew, Ji, Ru-Rong, Woolf, Clifford J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Society for Neuroscience 2005
विषय:
Behavioral/Systems/Cognitive
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725443/
https://ncbi.nlm.nih.gov/pubmed/16135755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2393-05.2005
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