Inhibition of cAMP Response Element-Binding Protein or Dynorphin in the Nucleus Accumbens Produces an Antidepressant-Like Effect

The cAMP response element-binding protein (CREB) is a critical integrator of neural plasticity that is responsive in a brain region-specific manner to a variety of environmental and pharmacological stimuli, including widely prescribed antidepressant medications. We developed inducible transgenic lin...

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Vydáno v:J Neurosci
Hlavní autoři: Newton, Samuel S., Thome, Johannes, Wallace, Tanya L., Shirayama, Yukihikko, Schlesinger, Lee, Sakai, Norio, Chen, Jingshan, Neve, Rachael, Nestler, Eric J., Duman, Ronald S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2002
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758459/
https://ncbi.nlm.nih.gov/pubmed/12486182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-24-10883.2002
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