Altered Responsiveness to Cocaine and Increased Immobility in the Forced Swim Test Associated with Elevated cAMP Response Element-Binding Protein Expression in Nucleus Accumbens

Drugs of abuse regulate the transcription factor cAMP response element-binding protein (CREB) in striatal regions, including the nucleus accumbens (NAc). To explore how regulation of CREB in the NAc affects behavior, we used herpes simplex virus (HSV) vectors to elevate CREB expression in this regio...

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Detalhes bibliográficos
Main Authors: Pliakas, Andrea M., Carlson, Richard R., Neve, Rachael L., Konradi, Christine, Nestler, Eric J., Carlezon, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205577/
https://ncbi.nlm.nih.gov/pubmed/11549750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-18-07397.2001
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