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Altered Responsiveness to Cocaine and Increased Immobility in the Forced Swim Test Associated with Elevated cAMP Response Element-Binding Protein Expression in Nucleus Accumbens

Drugs of abuse regulate the transcription factor cAMP response element-binding protein (CREB) in striatal regions, including the nucleus accumbens (NAc). To explore how regulation of CREB in the NAc affects behavior, we used herpes simplex virus (HSV) vectors to elevate CREB expression in this regio...

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Bibliografische gegevens
Hoofdauteurs: Pliakas, Andrea M., Carlson, Richard R., Neve, Rachael L., Konradi, Christine, Nestler, Eric J., Carlezon, William A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2001
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205577/
https://ncbi.nlm.nih.gov/pubmed/11549750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-18-07397.2001
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