Altered Sensitivity to Rewarding and Aversive Drugs in Mice with Inducible Disruption of cAMP Response Element-Binding Protein Function within the Nucleus Accumbens

The transcription factor cAMP response element-binding protein (CREB) within the nucleus accumbens (NAc) plays an important role in regulating mood. In rodents, increased CREB activity within the NAc produces depression-like signs including anhedonia, whereas disruption of CREB activity by expressio...

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Bibliografski detalji
Glavni autori: DiNieri, Jennifer A., Nemeth, Christina L., Parsegian, Aram, Carle, Tiffany, Gurevich, Vsevolod V., Gurevich, Eugenia, Neve, Rachael L., Nestler, Eric J., Carlezon, William A.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2009
Teme:
Brief Communications
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666984/
https://ncbi.nlm.nih.gov/pubmed/19211892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5104-08.2009
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