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Tissue Plasminogen Activator Mediates Microglial Activation via Its Finger Domain through Annexin II

Microglia are the immunocompetent cells of the CNS, and their activation is thought to play an important neurotoxic role in many diseases modeled by glutamate-induced excitotoxicity. One molecule whose expression is upregulated after excitotoxic injury is tissue plasminogen activator (tPA), a serine...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Siao, Chia-Jen, Tsirka, Stella E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758380/
https://ncbi.nlm.nih.gov/pubmed/11978811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-09-03352.2002
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