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Involvement of finger domain and kringle 2 domain of tissue-type plasminogen activator in fibrin binding and stimulation of activity by fibrin.

Human tissue-type plasminogen activator (t-PA) catalyses the conversion of inactive plasminogen into active plasmin, the main fibrinolytic enzyme. This process is confined to the fibrin surface by specific binding of t-PA to fibrin and stimulation of its activity by fibrin. Tissue-type plasminogen a...

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Bibliografski detalji
Glavni autori: Verheijen, J H, Caspers, M P, Chang, G T, de Munk, G A, Pouwels, P H, Enger-Valk, B E
Format: Artigo
Jezik:Inglês
Izdano: 1986
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1167389/
https://ncbi.nlm.nih.gov/pubmed/3030730
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