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The Role of Spinal Neuroimmune Activation in Morphine Tolerance/Hyperalgesia in Neuropathic and Sham-Operated Rats

Hypersensitivity resulting from nerve injury or morphine tolerance/hyperalgesia is predicted to involve similar cellular and molecular mechanisms. One expected but incompletely explored mechanism is the activation of central neuroimmune responses associated with these conditions. To begin to address...

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Pubblicato in:J Neurosci
Autori principali: Raghavendra, Vasudeva, Rutkowski, Maria D., DeLeo, Joyce A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757841/
https://ncbi.nlm.nih.gov/pubmed/12427855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-22-09980.2002
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