Brain-Derived Neurotrophic Factor Is Essential for Opiate-Induced Plasticity of Noradrenergic Neurons

Chronic opiate exposure induces numerous neurochemical adaptations in the noradrenergic system, including upregulation of the cAMP-signaling pathway and increased expression of tyrosine hydroxylase (TH), the rate-limiting enzyme in catecholamine biosynthesis. These adaptations are thought to compens...

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Publicat a:J Neurosci
Autors principals: Akbarian, Schahram, Rios, Maribel, Liu, Rong-Jian, Gold, Stephen J., Fong, Hiu-Fai, Zeiler, Steve, Coppola, Vincenzo, Tessarollo, Lino, Jones, Kevin R., Nestler, Eric J., Aghajanian, George K., Jaenisch, Rudolf
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2002
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ARTICLE
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757651/
https://ncbi.nlm.nih.gov/pubmed/12019333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-10-04153.2002
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