The cGAS/STING Pathway Is Important for Dendritic Cell Activation but Is Not Essential to Induce Protective Immunity against Mycobacterium tuberculosis Infection

Mycobacterium tuberculosis (Mtb) infection remains a major public health concern. The STING (stimulator of interferon genes) pathway contributes to the cytosolic surveillance of host cells. Most studies on the role of STING activation in Mtb infection have focused on macrophages. Moreover, a detaile...

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Publicat a:J Innate Immun
Autors principals: Marinho, Fabio V., Benmerzoug, Sulayman, Rose, Stephanie, Campos, Priscila C., Marques, João T., Báfica, André, Barber, Glen, Ryffel, Bernhard, Oliveira, Sergio C., Quesniaux, Valerie F.J.
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757162/
https://ncbi.nlm.nih.gov/pubmed/29791904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000488952
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