The cGAS/STING Pathway Is Important for Dendritic Cell Activation but Is Not Essential to Induce Protective Immunity against Mycobacterium tuberculosis Infection

Mycobacterium tuberculosis (Mtb) infection remains a major public health concern. The STING (stimulator of interferon genes) pathway contributes to the cytosolic surveillance of host cells. Most studies on the role of STING activation in Mtb infection have focused on macrophages. Moreover, a detaile...

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Detalhes bibliográficos
Publicado no:J Innate Immun
Main Authors: Marinho, Fabio V., Benmerzoug, Sulayman, Rose, Stephanie, Campos, Priscila C., Marques, João T., Báfica, André, Barber, Glen, Ryffel, Bernhard, Oliveira, Sergio C., Quesniaux, Valerie F.J.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757162/
https://ncbi.nlm.nih.gov/pubmed/29791904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000488952
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