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Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells

The accumulation of autophagosomes and dysfunction at the axonal terminal of neurons play crucial roles in the genesis and development of Alzheimer’s disease (AD). Abnormalities in neuron axonal transport-related proteins prevent autophagosome maturation in AD. Curcumin, a polyphenol plant compound,...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Liang, Jie, Zhou, Fanlin, Xiong, Xiaomin, Zhang, Xiong, Li, Shijie, Li, Xiaoju, Gao, Minna, Li, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756876/
https://ncbi.nlm.nih.gov/pubmed/31488728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102235
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