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Flux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and TrkB
Axonal retrograde transport of signalling endosomes from the nerve terminal to the soma underpins survival. As each signalling endosome carries a quantal amount of activated receptors, we hypothesized that it is the frequency of endosomes reaching the soma that determines the scale of the trophic si...
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| Gepubliceerd in: | Nat Commun |
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| Hoofdauteurs: | , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5427517/ https://ncbi.nlm.nih.gov/pubmed/27687129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12976 |
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