Control of Autophagosome Axonal Retrograde Flux by Presynaptic Activity Unveiled Using Botulinum Neurotoxin Type A

Botulinum neurotoxin type A (BoNT/A) is a highly potent neurotoxin that elicits flaccid paralysis by enzymatic cleavage of the exocytic machinery component SNAP25 in motor nerve terminals. However, recent evidence suggests that the neurotoxic activity of BoNT/A is not restricted to the periphery, bu...

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Publicado en:J Neurosci
Main Authors: Wang, Tong, Martin, Sally, Papadopulos, Andreas, Harper, Callista B., Mavlyutov, Timur A., Niranjan, Dhevahi, Glass, Nick R., Cooper-White, Justin J., Sibarita, Jean-Baptiste, Choquet, Daniel, Davletov, Bazbek, Meunier, Frédéric A.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2015
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787026/
https://ncbi.nlm.nih.gov/pubmed/25878289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3757-14.2015
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