A Cell Line for Detection of Botulinum Neurotoxin Type B

Botulinum neurotoxins (BoNTs) type A and type B are commonly used as biopharmaceutics for neurological diseases, uniquely allowing months-long paralysis of target muscles. Their exquisite neuronal specificity is conferred by a multistep process of binding, internalization, cytosolic escape and cleav...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Rust, Aleksander, Doran, Ciara, Hart, Rosalyn, Binz, Thomas, Stickings, Paul, Sesardic, Dorothea, Peden, Andrew A., Davletov, Bazbek
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684488/
https://ncbi.nlm.nih.gov/pubmed/29170639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00796
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