Estrogen-dependent DLL1-mediated Notch signaling promotes luminal breast cancer

Aberrant Notch signaling is implicated in several cancers, including breast cancer. However, the mechanistic details of the specific receptors and function of ligand-mediated Notch signaling that promote breast cancer remains elusive. In our studies we show that DLL1, a Notch signaling ligand, is si...

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Pubblicato in:Oncogene
Autori principali: Kumar, Sushil, Srivastav, Ratnesh Kumar, Wilkes, David W., Ross, Taylor, Kim, Sabrina, Kowalski, Jules, Chatla, Srinivas, Zhang, Qing, Nayak, Anupma, Guha, Manti, Fuchs, Serge Y., Thomas, Christoforos, Chakrabarti, Rumela
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756232/
https://ncbi.nlm.nih.gov/pubmed/30442981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0562-z
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