Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo

The Notch ligands Dll1 and Dll3 are coexpressed in the presomitic mesoderm of mouse embryos. Despite their coexpression, mutations in Dll1 and Dll3 cause strikingly different defects. To determine if there is any functional equivalence, we replaced Dll1 with Dll3 in mice. Dll3 does not compensate fo...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Geffers, Insa, Serth, Katrin, Chapman, Gavin, Jaekel, Robert, Schuster-Gossler, Karin, Cordes, Ralf, Sparrow, Duncan B., Kremmer, Elisabeth, Dunwoodie, Sally L., Klein, Thomas, Gossler, Achim
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2007
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064846/
https://ncbi.nlm.nih.gov/pubmed/17664336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200702009
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi