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Unbalanced YAP–SOX9 circuit drives stemness and malignant progression in esophageal squamous cell carcinoma
Yes-associated protein (YAP) has been identified as a key regulator of tissue homeostasis. However, the precise role and regulatory mechanism of YAP in esophageal squamous cell carcinoma (ESCC) remains unclear. Here we report that the genetic or pharmacological inhibition of YAP repressed cancer ste...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6756096/ https://ncbi.nlm.nih.gov/pubmed/30401982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0476-9 |
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