The NF2 tumor suppressor merlin interacts with Ras and RasGAP, which may modulate Ras signaling

Inactivation of the tumor suppressor NF2/merlin underlies neurofibromatosis type 2 (NF2) and some sporadic tumors. Previous studies have established that merlin mediates contact inhibition of proliferation; however, the exact mechanisms remain obscure and multiple pathways have been implicated. We h...

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Bibliografiske detaljer
Udgivet i:Oncogene
Main Authors: Cui, Yan, Groth, Susann, Troutman, Scott, Carlstedt, Annemarie, Sperka, Tobias, Riecken, Lars Björn, Kissil, Joseph L., Jin, Hongchuan, Morrison, Helen
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756068/
https://ncbi.nlm.nih.gov/pubmed/31312020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0883-6
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