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The NF2 tumor suppressor merlin interacts with Ras and RasGAP, which may modulate Ras signaling
Inactivation of the tumor suppressor NF2/merlin underlies neurofibromatosis type 2 (NF2) and some sporadic tumors. Previous studies have established that merlin mediates contact inhibition of proliferation; however, the exact mechanisms remain obscure and multiple pathways have been implicated. We h...
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| Veröffentlicht in: | Oncogene |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6756068/ https://ncbi.nlm.nih.gov/pubmed/31312020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0883-6 |
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