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Manipulation of the Sphingolipid Rheostat Influences the Mediator of Flow‐Induced Dilation in the Human Microvasculature

BACKGROUND: Elevated levels of ceramide, a sphingolipid known to cause a transition from nitric oxide (NO)– to hydrogen peroxide–dependent flow‐induced dilation (FID) in human arterioles, correlate with adverse cardiac events. However, elevations of ceramide are associated with changed concentration...

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Dades bibliogràfiques
Publicat a:J Am Heart Assoc
Autors principals: Schulz, Mary E., Katunaric, Boran, Hockenberry, Joseph C., Gutterman, David D., Freed, Julie K.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755855/
https://ncbi.nlm.nih.gov/pubmed/31462128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.013153
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