Critical Role for Telomerase in the Mechanism of Flow-Mediated Dilation in the Human Microcirculation

RATIONALE: Telomerase is a nuclear regulator of telomere elongation with recent reports suggesting a role in regulation of mitochondrial reactive oxygen species. Flow-mediated dilation in patients with cardiovascular disease is dependent on the formation of reactive oxygen species. OBJECTIVE: We exa...

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Dettagli Bibliografici
Pubblicato in:Circ Res
Autori principali: Beyer, Andreas M., Freed, Julie K., Durand, Matthew J., Riedel, Michael, Ait-Aissa, Karima, Green, Paula, Hockenberry, Joseph C., Morgan, R. Garret, Donato, Anthony J., Peleg, Refael, Gasparri, Mario, Rokkas, Chris K., Santos, Janine H., Priel, Esther, Gutterman, David D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2016
Soggetti:
Clinical Track
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772813/
https://ncbi.nlm.nih.gov/pubmed/26699654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.307918
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