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Inositol phosphates and core subunits of the Sin3L/Rpd3L histone deacetylase (HDAC) complex up-regulate deacetylase activity

The constitutively nuclear histone deacetylases (HDACs) 1, 2, and 3 erase acetyl marks on acetyllysine residues, alter the landscape of histone modifications, and modulate chromatin structure and dynamics and thereby crucially regulate gene transcription in higher eukaryotes. Nuclear HDACs exist as...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Marcum, Ryan Dale, Radhakrishnan, Ishwar
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755813/
https://ncbi.nlm.nih.gov/pubmed/31358618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009780
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