Structures of CENP-C cupin domains at regional centromeres reveal unique patterns of dimerization and recruitment functions for the inner pocket

The successful assembly and regulation of the kinetochore are critical for the equal and accurate segregation of genetic material during the cell cycle. CENP-C (centromere protein C), a conserved inner kinetochore component, has been broadly characterized as a scaffolding protein and is required for...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Chik, Jennifer K., Moiseeva, Vera, Goel, Pavitra K., Meinen, Ben A., Koldewey, Philipp, An, Sojin, Mellone, Barbara G., Subramanian, Lakxmi, Cho, Uhn-Soo
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2019
Sujets:
Protein Structure and Folding
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755791/
https://ncbi.nlm.nih.gov/pubmed/31366733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008464
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