Structures of CENP-C cupin domains at regional centromeres reveal unique patterns of dimerization and recruitment functions for the inner pocket

The successful assembly and regulation of the kinetochore are critical for the equal and accurate segregation of genetic material during the cell cycle. CENP-C (centromere protein C), a conserved inner kinetochore component, has been broadly characterized as a scaffolding protein and is required for...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chik, Jennifer K., Moiseeva, Vera, Goel, Pavitra K., Meinen, Ben A., Koldewey, Philipp, An, Sojin, Mellone, Barbara G., Subramanian, Lakxmi, Cho, Uhn-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755791/
https://ncbi.nlm.nih.gov/pubmed/31366733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008464
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